Science magazine finally catches up with the Science 2 years later
T cells do play an important role
Another “conspiracy theory” that would get you suspended on social media was that if you had been previously infected, memory T cells would help protect you against future disease.
Anyone with an ounce of critical thinking capacity asked, “if I have already had Covid, why would I need to get vaccinated? Why not give the vaccine to someone who might need it or just not buy my dose in the first place?” The High Priests of The Science™ would then begin their gaslighting, trying to convince you that natural immunity does not exist and that vaccination is the only way to protect yourself.
However, as with most recent “conspiracy theories”, this one is again proven to be true and the High Priests, unable to hide these facts, quickly switch to gaslighting again. This time, gaslighting that they knew this stuff the whole time and it has all been some gigantic misinterpretation.
The latest article in Science, whilst still focussing on vaccines, acknowledges the important role T cells play. They say “accumulating data suggest that T cell responses play an important role in vaccine protection against severe COVID-19 disease, particularly against viral variants that partially escape from recognition by NAbs.”
The article explains that there are two arms of the adaptive immune system that produce protective immunity. Humoral immunity provided by antibodies & memory B cells and cellular immunity provided by T cells. If antibodies are present in the body in high enough volumes, they can block infection. This was their hope for the vaccines but it clearly didn’t work.
T cells only recognise viruses once they are in the host cells. Therefore, whilst they probably don’t prevent infection they are likely to prevent severe disease.
If virus breaches NAb defenses in the upper respiratory tract, protection from severe disease could still be mediated if immune mechanisms prevent virus spread to the lower respiratory tract and control virus replication in the lungs. Such protection can involve antibodies, but T cells are ideally suited to limit virus replication by eliminating virus-infected cells.
memory T cells can rapidly elaborate effector functions to suppress viral replication, limit infection, and prevent spread within the host. For example, CD8+ T cells directly kill infected cells and produce antiviral cytokines, as well as inflammatory molecules that recruit additional immune cells to sites of infection.
The “conspiracy theorists” insisted that T cells would help protect you long after your Covid infection but maybe the High Priests were correct when they said that protection was short-lived and so vaccination was still necessary?
According to this paper, no. “Once generated, memory T cells can be stably maintained for decades in humans, and SARS-CoV-2-specific memory T cells durably persist after vaccination or infection.”
Remember when the “conspiracy theorists” said mass vaccination could force the virus to evolve? Again, according to this paper “immune pressure from antibodies is likely driving evolution of the spike protein, resulting in incomplete neutralization of new viral variants by NAbs induced by vaccination or infection”.
Yes, antibodies from natural infection drive evolution but not as much as someone who has extremely high levels of antibodies from vaccination, three times in the same year.
Remember when the “conspiracy theorists” said it is better to get a broad immune response, rather than the specific vaccine one targeted at the Wuhan spike protein? Fortunately, the broad T cell response remains largely intact against all variants. Even if a mutation occurs causing escape “from T cell immunity in one person [it] is unlikely to do so in another person. Overall, emerging viral variants substantially affect antibody neutralization but so far have had a minimal impact on T cell responses.”
Whatever your views on the vaccines are, why was discussing this information on natural immunity and T cells supressed and why were people who had previously been infected told to get vaccinated.